Sponsored: If you’re a researcher looking to incorporate TB-500 into your work, this guide will provide you with the latest information on TB-500′s mechanism of action, uses, and side effects.
TB-500 is a synthetic version of the naturally occurring peptide thymosin beta-4, aka timbetasin. Research on TB-500 usually refers to it as synthetic thymosin beta-4.
Human studies on TB-500 are lacking, but the peptide is the subject of active research due to the regenerative properties of thymosin beta-4.
Thymosin beta-4 is found in every cell in the human body except erythrocytes, and is thought to play a role in angiogenesis, wound healing, and cell proliferation, differentiation, and migration.
If you’re a researcher looking to incorporate TB-500 into your work, this guide will provide you with the latest information on TB-500′s mechanism of action, uses, and side effects.
We also include details on how to dose and administer TB-500 in research settings, as well as where to source 99% purity TB-500 online.
P.S: Order TB-500 online here!
What is TB-500?
TB-500 is a synthetic form of thymosin beta-4 (TB4), an endogenous human peptide that is made of 43 amino acids and can be found in virtually all cells of the body, especially in platelets and white blood cells [1]. TB4 was first isolated in 1981 by Low and Goldstein from bovine thymus gland extract [2].
The synthetic version, TB-500, has not been approved for human use and is available solely as a research chemical. It was first manufactured in the early 2010s for veterinary use. TB-500 has been used as a doping agent in horse racing and consecutively banned for providing an unfair advantage in that sport [3, 4].
Thymosin beta-4 and its derivatives, including TB-500, are likewise banned by the World Anti-Doping Agency (WADA) and thus prohibited for use by competitive athletes subject to the WADA Code and comparable national and regional regulatory bodies [5].
TB-500 is nonetheless under active research for its potential effects on cell migration and tissue repair, formation of new blood vessels, maturation of stem cells, survival of various cell types, and anti-inflammatory action [1, 6].
TB-500 and thymosin beta-4 have poor oral bioavailability, and thus can only be administered via injections in experimental settings.
Yet, a naturally occurring fragment of thymosin beta-4, called N-acetyl seryl-aspartyl-lysyl-proline (Ac-SDKP), is an orally active peptide thought to possess similar antifibrotic, anti-inflammatory, angiogenic properties, and effects on cell migration and survival [7, 8].
It has been investigated as an inhibitor of hematopoietic stem cell proliferation and a chemoprotective agent [9, 10]. Researchers may find the TB-500 fragment included in innovative TB-500 capsule formulas intended for tissue repair and recovery.
TB-500 Dosage Calculator and Chart
It’s worth noting that due to the lack of published research on TB-500, there are currently no specific dosage recommendations for research purposes.
The available research primarily involves animal models or test subjects, and the findings from these studies cannot be directly applied to humans.
The limited human studies conducted with injectable thymosin beta-4 report TB-500 dosing that varies greatly and administered at a maximum duration of 14 days. There are no clinical studies involving TB-500 peptide therapy courses longer than two weeks [29, 30].
Alternatively, thymosin beta-4 has also been effectively used topically in clinical trials at concentrations of 0.03% for over three months. Topical use has also shown excellent safety and tolerability [20].
Based on current information, TB-500 injections for injury recovery may be administered based on the following schedule:
- TB-500 Daily Dose: 2mg, administered subcutaneously
- Study Duration: 15 days
- Notes: Three vials of TB-500 10mg are required to complete this protocol. Following the two week period, researchers may continue administering a daily maintenance dose of 1mg, as needed, to achieve full or near-full recovery.
For more detailed information on TB-500 dosing, see our detailed TB-500 Dosage Calculator and Chart.
Where to Buy TB-500 Online?
When procuring TB-500 online for research purposes, peptide buyers should meticulously assess different vendors in regards to pricing, dependability, customer reviews, product quality, accepted payment methods, and the level of customer service offered.
Based on our extensive experience, we wholeheartedly endorse Peptide Sciences as a reliable source for research-grade TB-500. Their track record of consistently delivering quality products makes them an excellent choice for researchers seeking TB-500 online.
Post time: Dec-06-2023